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Vollenweider Krähenmann

Fakultäten » Medizinische Fakultät » Psychiatrische Universitätsklinik » Psychiatrie, Psychotherapie und Psychosomatik, Klinik für » Prof. Dr. F. X. Vollenweider » Vollenweider Krähenmann

Completed research project

Title / Titel Visual Organization Processing in Schizophrenia. A Behavioral Study
PDF Abstract (PDF, 14 KB)
Summary / Zusammenfassung Visual anomalies, ranging from unusual visual perceptual experiences to visual hallucinations, are commonly found in schizophrenic patients. Recent studies have shown that visual processes which organize retinal input into higher-level percepts are particularly impaired in schizophrenia. Our group has only lately given evidence for visual organization deficits in psilocybin-induced model psychosis and found them to be associated with visual hallucinations (Kometer et al. 2010, in press). It is unclear, however, whether visual organization deficits in schizophrenia encompass the whole visual field. Moreover, it is still not known whether shape and contour organization – crucial processes in object recognition - are impaired in schizophrenia and how visual organization deficits relate to altered cognition and perceptual anomalies. Our study aims at answering these questions by measuring psychophysically the discrimination of illusory and peripheral visual objects in schizophrenic patients compared to matched healthy controls. Furthermore, we investigate the relationship between behavioral measures of such processes on the one hand and cognitive alterations and perceptual disturbances on the other hand.
Publications / Publikationen Kometer, M., Cahn, B.R., Andel, D., Carter, O. & Vollenweider, F.X. The 5-HT2A/1A agonist psilocybin disrupts modal object completion associated with visual hallucinations. Biological Psychiatry, 2010, in press
Keywords / Suchbegriffe Schizophrenia; Visual Processing; Organization; Cognition; Perception; Visual Hallucinations; Illusory; Peripheral; Human Behavioral Study
Project leadership and contacts /
Projektleitung und Kontakte
Prof. F.X. Vollenweider (Project Leader) vollen@bli.uzh.ch
Dr. R. Krähenmann (Project Leader) Rainer.Kraehenmann@puk.zh.ch
MS M. Kometer  
Prof. E. Seifritz  
Funding source(s) /
Unterstützt durch
Foundation
 
Duration of Project / Projektdauer Nov 2010 to Dec 2012