Latal Bucher
Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Entwicklungspädiatrie, Abteilung » PD Dr. Oskar Jenni » Latal Bucher
Completed research project
| Title / Titel | Prediction of neurodevelopment outcome in very preterm infants using cerebral function monitoring | ||||
|---|---|---|---|---|---|
| Abstract (PDF, 14 KB) | |||||
| Summary / Zusammenfassung | Preterm infants constitute a population with a high risk for cerebral injury and thus neurodevelopmental impairments. Prognosis of the outcome is based on neurological, electrophysiological and neuroradiological findings. Cerebral function monitoring (CFM) is a non - invasive device, which can be used easily as a bedside monitoring. It provides immediate information on brain activity and may confirm clinical seizures as well as detect subclinical seizures. CFM is a critical tool in the evaluation of term newborns with hypoxic-ischemic encephalopathy. In preterm infants, CFM has not been used routinely. Little information is available on the association between CFM and other measures of cerebral function and cerebral neurostructure as well the predictive strenght of CFM on neurodevelopmental outcome. In addition, CFM may serve to monitor the treatment effect in newborns treated with EPO to reduce brain injury. The aim of the present study is to determine the predictive strength of CFM regarding other biomarkers of neurodevelopment as well as regarding neurodevelopmental outcome in a prospectively enrolled population of preterm infants born before the 32nd week of gestation. |
||||
| Keywords / Suchbegriffe | amplitude integrated EEG, preterm, infant, neurodevelopment | ||||
| Project leadership and contacts / Projektleitung und Kontakte |
|
||||
| Funding source(s) / Unterstützt durch |
SNF (Personen- und Projektförderung) Part of a SPUM Project |
||||
| In collaboration with / In Zusammenarbeit mit |
|
||||
| Duration of Project / Projektdauer | Jan 2009 to Oct 2012 |