Prof. Dr. Haiko Sprott - Molecular mechanisms of osteoarthritic joint pain

Fakultäten » Medizinische Fakultät » Rheumaklinik und Institut für physikalische Medizin » Prof. Dr. Haiko Sprott

Current research projects

Project leader	Project title
Sprott	Functional genomic studies of pain in knee osteoarthritis
	Effectiveness of radiofrequency denervation of zygapophysial joints in the treatment of chronic back pain over a period of twelve months

Completed research projects

Project leader	Project title
Mannion	Cross-cultural adaptation and validation of a German version of the Pain Catastrophising Scale for use in patients with chronic low back pain
Mannion Sprott	Development of a clinical prediction rule to identify patients with chronic low back pain who respond positively to spine stabilisation exercises.
Sprott	Functional role of P2X4 purinoceptor and of Brain Derived Neurotrophic Factor (BDNF) in chronic arthritic pain: Investigation in synovial tissues and cultures of synovial fibroblasts from patients with knee osteoarthritis and rheumatoid arthritis.
	Molecular and cellular studies of pain receptors and neuropeptides in different conditions of chronic pain.
	Can Tissue Doppler Imaging distinguish between the function of Musculus transversus abdominis in patients with chronic non-specific low back pain and healthy controls?
	Influence of an outpatient multidisciplinary pain management program on the health-related quality of life and the physical fitness of chronic pain patients.
	Microcirculation in Fibromyalgia.
Sprott Aeschlimann	Can pain molecules in serum and in the synovial fluids of patients with inflammatory joint diseases be used to differentiate their disease aetiology?
Sprott Mannion	Development of a non-invasive, ultrasound-based tool for the assessment of voluntary and anticipatory activation of M. transversus abdominis in patients with chronic low back pain: reliability, validity and sensitivity to change after a programme of spine stabilisation exercises
	Transversus abdominis contraction ratio during abdominal hollowing: a valid tool to identify patients with chronic low back pain?
	Assessing outcome after physical therapy for chronic low back pain: tailor-made or off-the shelf instruments?
	Ultrasound tissue Doppler imaging reveals no delay in abdominal muscle feed-forward activity during rapid arm movements in patients with chronic low back pain.