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Prof. Dr. Gerd Kullak-Ublickmore information

Fakultäten » Medizinische Fakultät » Klinische Pharmakologie und Toxikologie, Klinik für » Prof. Dr. Gerd Kullak-Ublick

Current research projects

Project leader Project title
Egbring Predictive models to identify patients at risk for drug-related adverse outcomes
Kullak-Ublick Role of drug transporters and nuclear receptors in drug-induced liver and kidney injury
Merz Translational Safety Biomarker Pipeline (TransBioLine): enabling development and implementation of novel safety biomarkers in clinical trials and diagnosis of disease
Stieger Role of Membrane Lipid Environment on the Transport Activity of Hepatocellular Organic Anion Transporters

Completed research projects

Project leader Project title
Ceschi PLANT food supplements: Levels of Intake, Benefit and Risk Assessment
Egbring Randomized controlled study to evaluate the interventional use of the drug prescription application EPha.ch
Eloranta Regulation of genes encoding drug transporters of the SLC family by xenobiotic and oxidative stress-responsive transcription factors in the liver, intestinal, and kidney cells
Fattinger Pharmacokinetics of Diacetylmorphine in Narcotic Addicts
Hagenbuch Molecular physiology of bile acid, organic anion and drug transport within the enterohepatic circulation
Physiological and molecular characterization of multispecific organic anion transporting polypetides
Jetter Dose-effect relationship between allopurinol, azathioprine and 6-thioguanine nucleotide levels (6-TGN) in inflammatory bowel disease patients.
Genetic influences on the inducibility of cytochrome P450 enzymes.
Kullak-Ublick Regulation and expression of drug and bile acid transporters in liver and intestine: implications for drug disposition in health and in liver disease
SAFE-T Consortium: Safer and Faster Evidence-based Translation
Drug-induced liver and kidney injury in obesity
Drug and organic anion transport by human liver: pharmacological characterization, analysis of expression and genetic regulation of hepatocellular organic anion transporting proteins (OATPs)
Functional characterization and transcriptional regulation of drug and bile acid transporters in human liver and intestine
Swiss Inflammatory Bowel Disease Cohort Study (SIBDCS)
Regulation and genetic variability of drug and organic anion transporter genes: implications for liver and intestinal diseases
Regulation and functional characterization of transporters for drugs and endogenous substances in the human intestine
Barrett's Esophagus: role of transcription factors CDX1 and CDX2 in diagnosis and molecular pathogenesis
ProDoc: Regulation of genes encoding metabolizing enzymes and drug transporters by xenobiotic- and oxidative stress-responsive transcription factors
NCCR-Kidney.CH: Control of nutrient and drug bioavailability by the kidney: impact of uninephrectomy on drug and bile acid transport
Molecular and Functional characterization and Regulation of Expression of Drug and Organic Anion Uptake Systems in Human Liver
Meier-Abt Molecular Physiology and Pathophysiology of Hepatic Bile Formation and Cholestatic Liver Disease
Mechanisms of Canalicular Bile Salt and Cholesterol Secretion
Meier-Abt Fattinger Drug Safety in Inpatients / Comprehensive Hospital Drug Monitoring CHDM: Pharmacoepidemiologic Research Database on Medical Inpatients
Pauli Magnus Effect of Ritonavir on the Pharmacokinetics of the Benzimidazoles Albendazole and Mebendazole
St-Pierre The identification of transporters involved in steroidogenesis in the materno-fetal-placental unit.
Stieger Molecular Mechanisms of Canalicular bile Formation: Role of Novel Phospholipid Flippases and Drug Uptake Mechanisms
Role of Skeletal Muscle Transport Systems in Statin-induced Myotoxicity
Optimization and pre-validation of an in vitro test strategy of predicting human acute toxicity. EU contract no.: FP6-512051 WP 7.3: Hepatotoxicity, partner no. 28
Molecular physiology of bile formation: acute regulation of canalicular bile salt and organic anion secretion and relation to canalicular lipid secretion
The Role of Microdomains in Canalicular Bile Formation
ProDoc: Role of skeletal muscle transport systems in statin-induced myotoxicity
NCCR Transcure: Role of canalicular lipid secretion in acquired forms of cholestasis
Stieger Stieger Identification of Transport Systems for the PET Imagin Tracer Flurocholine
Stieger Meier-Abt Hepatocyte Transplantation for End Stage Liver Disease: Potential of Hepatocyte Progenitor Cells and Bone Marrow Stem Cells
Trojan Impact of genetic polymorphisms in CYP (cytochrome P450) genes on the outcome of treatment with tamoxifen in breast cancer patients
Vavricka Role of bacteria-derived peptides in intestinal epithelial cells in health and in patients with inflammatory bowel disease


Last update 12.06.2019